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Stretch marks are called stria atrophicae in the field of dermatology. They are often characterized as scarring on the skin due to weight gain. They appear on body parts where higher amounts of fats are accumulated. Such body parts are the thighs, hips, buttocks, and the abdomen.

Stretch marks are produced from the over-stretching of the middle layer of the skin namely, the dermis. This layer stretches to its maximum capability to be able to fit a larger body. This would result to microscopic bleeding and tissue inflammation and would manifest as reddish-purple lines on the skin. Also, this would cause the outer layer of the skin to expand making the lines visible enough. The stretch marks would appear once these lines heal and would have a shade lighter than the natural skin tone.

Some studies suggest that glucocorticoids, a group of steroids, are associated with stretch marks. Cortisol is the most common example of a glucocorticoid. Research showed that when the body is at stress, it releases cortisol at a level above its normal amount. This could halt fibrolasts from forming elastin fibers and collagen, which are essential for keeping a new skin firm. This would ultimately lead to the tearing of the epidermal and dermal layer due to lack of these supporting materials.

Numerous studies have been made regarding procedures on how to prevent or remove stretch marks. The use of retinoid creams or alpha-hydroxy acid, mixed with tropical steroids, were proven to prevent stretch marks.

Steroids are able to reduce inflammation such as the inflammation caused by the stretching of the dermis. Retinoids or alpha-hydroxy acids counter-act the negative effects of steroids. Thus, this combination could help prevent the formation of stretch marks.

Other methods are available to make existing stretch marks barely there, including laser treatments, dermabrasion, and prescription retinoids. Dermabrasion is a cosmetic procedure in which the stratum corneum (outer surface of the epidermis) is being removed by abrasion, or sanding, targeting sun-damaged skin and dark spots on the skin. A laser treatment, called fractional laser resurfacing, uses pulses of light that creates microscopic wounds on the scar. In which, body produces new collagen and epithelium that improves the texture and appearance of mature stretch marks.

Another method uses a surgical procedure, the tummy tuck. In here, the part of skin below the navel is being removed because this is where stretch marks oftenly form.